To fulfill the requirements of the Head Start for School Readiness Act of 2007, the Missouri Head Start State Collaboration Office (MHSSCO) has engaged in various processes to annually assess the needs of Head Start grantees and delegates in Missouri. Results of the needs assessment are used to better address issues faced by young children (birth to school entry) and their families with low income. For the 2022 needs assessment, the MHSSCO chose to continue its focus on Workforce Development and Partnerships within State Systems priority areas. It builds on the information collected in Federal Fiscal Years 2018 through 2021 to address the needs of Missouri Head Start programs. MHSSCO will update its five-year strategic plan to guide its role in supporting Missouri Head Start programs based on these findings. (author abstract)