The purpose of this brief is to describe how Head Start responded to the COVID-19 pandemic by examining the challenges grantees faced, how they pivoted to address these challenges, and the supports they received from the OHS to serve the children and families in their care. The study findings can inform the field, help federal and state leaders develop or refine future supports for Head Start and Early Head Start grantees, and guide research on the impact of the COVID-19 pandemic on the CCEE system. (author abstract)