Young children's development during the first five years of life is rapid and varied between children and across domains (social-emotional, physical, cognitive, and linguistic) within a child. Early and frequent screening ensures children's healthy growth and development. Using reliable, valid, and appropriate screening tools provides important information to ensure children are meeting critical developmental milestones and may detect developmental issues for further evaluation, early intervention and treatment. This Topic of Interest highlights resources on developmental screening and assessment from the Research Connections collection that provide research-based information on: the critical elements of developmental screening and available tools, policy strategies to support developmental screening, and use of screening and assessment data to inform individualized learning plans in early care and education settings. (author abstract)