Toolkit Guidance: "2Gen Tools to Help Families and Children Thrive: A Resource for Staff Implementing Federal, State and Local Government Staff Programs Serving Children and Families" is intended to support Federal, State, and local program directors, policy experts, program specialists, research analysts, training and technical assistance staff, grants and budget analysts and other staff in how to embed a 2Gen approach in new funding opportunities; reviewing applications; designing programs, initiatives and priorities; developing policy guidance; and designing both internal professional development as well as providing technical assistance to grantees. The toolkit builds on a number of field resources (listed in the Appendix) including, "Two Generation Approaches," developed for and funded by ED. The toolkit includes resources to support a 2Gen approach and is organized into four main topics: 1 Developing or expanding initiatives and priorities; 2 Developing funding announcements; 3 Providing technical assistance to existing grantees; and 4 Creating or building a research agenda for Federal 2Gen initiatives. In each section, there is information on key principles and guidance in enhancing and strengthening the 2Gen approach. The toolkit is intended to serve as a quick and easy reference with guiding questions and several checklists, tailored to a variety of staff, to embed 2Gen approaches. The toolkit ends with communication tips to share with colleagues as well as grantees. (author abstract)