Throughout 2020 and much of 2021, the COVID-19 pandemic forced Head Start programs across the country to make major changes to center operations and services to keep children, families, and staff members safe. Yet even in the face of the pandemic, Head Start continued to support families at a time when many families needed the help. This brief, based on a small sample of six case studies conducted in fall 2020 as part of an MDRC study called Head Start Connects, outlines how Head Start programs responded to the ever-evolving public health emergency—shifting many activities to virtual formats, adapting in-person activities to local restrictions, and maintaining connections with families and community providers. (author abstract)